MULTIPLE-OMICS ANALYSIS OF AGGREPHAGY-RELATED CELLULAR PATTERNS AND DEVELOPMENT OF AN AGGREPHAGY-RELATED SIGNATURE FOR HEPATOCELLULAR CARCINOMA

Multiple-omics analysis of aggrephagy-related cellular patterns and development of an aggrephagy-related signature for hepatocellular carcinoma

Abstract Background Protein aggrephagy, a selected autophagy process response for degrading protein aggregates, plays a critical role in various cancers.However, its regulatory mechanisms and clinical implications in hepatocellular carcinoma (HCC) remain largely unexplored.Methods We integrated bulk RNA-seq data from TCGA and single-cell RNA sequen

read more

The Rural Space - Support in Developing and Diversifying the Tourist Activities through Cultural and Economic Convergence

The study focuses on highlighting the current status of rural tourism and of the tendencies in its development in terms of some tourist indicators and the relationship between malibu relaxer them and the tourist potential of the parishes, even from the disadvantaged areas.The inquiry of the statistics data and of the different situations at the lev

read more